Scale Up

Nov 03, 2014
BioPharm International
By BioPharm International Editors
For cellular therapies to become a viable treatment for large-sized patient groups, steps need to be taken to develop an efficient manufacturing and supply system to minimise the cost of goods.
Mar 01, 2014
BioPharm International
The targeted delivery of cytotoxic drugs using antibody drug conjugates would not be possible without effective linkers to connect and then release the key chemical and biological materials.
Sep 01, 2013
BioPharm International
By BioPharm International Editors
Novasep's Sius single-use tangential flow filtration skid offers a 100% single-use TFF solution.
Aug 16, 2013
EMD Millipore and PharmaCell have entered into a collaboration to develop optimized large-scale expansion and harvest of HepaRG cells using bioreactor technology.
May 23, 2013
By BioPharm International Editors
Project will optimize expansion and harvest of human cells in bioreactors.
Dec 01, 2012
BioPharm International
The authors describe the development of an ultra scale-down anion exchange membrane adsorber, and demonstrate scalability to larger-scale devices.
Nov 01, 2012
BioPharm International
By BioPharm International Editors
Scaling up stem-cell cultures requires careful consideration of the bioreactor design.
Jul 01, 2012
BioPharm International
The authors present scale-up from a 5-L fermentor to a 50-L pilot-scale using the criterion of constant power consumption per unit liquid volume.
Jul 01, 2011
BioPharm International
The authors describe challenges faced in transfer and scale-up of a fermentation process.
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