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The Future of Monoliths and Chips: Monoliths have received renewed attention in the past few years. Will they — or chip-based columns — ever compete with particle-based columns? In a short video interview, Dick Henry weighs in.


  • RESOURCE: Total Water Solutions Guide: A tool to guide you through the major steps in every pure water installation project, helping you to design and configure the most efficient total pure water system.

  • VIDEO: LC–MS System:Check out this video of the triple quad LCMS-8050, which features ultrafast polarity switching (5 msec), an ultra-high-speed scan rate of 30,000 u/sec, and up to 555 MRMs/second.

  • VIDEO: The Pros and Cons of GCxGC: In a new interview, Frank L. Dorman of Penn State University talks about the evolution of GCxGC and the key advantages and disadvantages of the technique, including why fear of its complexity gets in the way of its broader use.

  • RESOURCE: Method Transfer from HPLC to UHPLC:The Analysis of Fullerenes by Liquid Chromatography Mass Spectrometry.

  • LGCC TV: Mary Ellen McNally on Common Error with Internal Standard Methods.

  • TRAINING: CHROMacademy:Chromatography and Mass Spectrometry training covering subjects such as HPLC, GC, SPE, Mass Spec, and HILIC.

  • LCGC Video Library>>

Sponsored by: EMD Millipore, Shimadzu, Thermo Fisher Scientific, CHROMacademy.


Sample Prep Perspectives | Ronald E. Majors:

LCGC Columnist Ron Majors, established authority on new column technologies, keeps readers up-to-date with new sample preparation trends in all branches of chromatography and reviews developments in existing technology lines.

LATEST: The Role of Selectivity in Extractions: A Case Study

History of Chromatography | Industry Veterans:

With each installment of this column, a different industry veteran covers an aspect of the evolution and continued development of the science of chromatography, from its birth to its eventual growth into the high-powered industry we see today.

LATEST: Georges Guiochon: Separation Science Innovator

MS — The Practical Art| Kate Yu:
Kate Yu is the editor of 'MS-The Practical Art' bringing her expertise in the field of mass spectrometry and hyphenated techniques to the pages of LCGC. In this column she examines the mass spectrometric side of coupled liquid and gas-phase systems. Troubleshooting-style articles provide readers with invaluable advice for getting the most from their mass spectrometers.

LATEST: Mass Spectrometry for Natural Products Research: Challenges, Pitfalls, and Opportunities

LC Troubleshooting | John Dolan:

LC Troubleshooting sets about making HPLC methods easier to master. By covering the basics of liquid chromatography separations and instrumentation, John Dolan, Vice President of LC Resources and world renowned expert on HPLC, is able to highlight common problems and provide remedies for them.

LATEST: LC Method Scaling, Part I: Isocratic Separations

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Two-Dimensional LC in Pharmaceutical Analysis
Kelly Zhang of Genentech talks about the advantages gained by developing a two-dimensional LC method for analyzing impurities in pharmaceuticals, as well as the challenges in developing the method.
UHPLC Method Development and Modelling in the Framework of Quality by Design
The goals in ultrahigh-pressure liquid chromatography (UHPLC) method development are to first find the best separation, second find the best column, and third find the most robust method in a multifactorial Design Space. Trial and error methods are not sufficient anymore and solid science based on Quality by Design (QbD) principles is required.
The Storage and Use of Gases for Gas Chromatography
A discussion on the safe storage and use of calibration, carrier, and detector gas cylinders for small or large organizations.
The 2014 LCGC Awards
The winners of LCGC's seventh annual awards are highlighted.
New Chromatography Columns and Accessories at Pittcon 2014, Part I
New product introductions in the areas of HPLC columns for reversed-phase LC, HILIC, ion-exchange and ion chromatography, SEC, and specialty columns for specific types of analyses are covered.


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