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Hui Xiang
Articles
Establishing Process Design Space for a Chromatography Purification Step: Application of Quality-by-Design Principles
This case study reviews how quality-by-design principles can be implemented in an intermediate chromatography purification step that uses cation-exchange chromatography.Abstract
Minimization of Freeze/Thaw-Induced Protein Aggregation and Optimization of a Drug Substance Formulation Matrix
The authors explore the use of statistical experimental design and multivariate analysis to develop a drug substance formulation matrix.