BioPharm International Supplements, November 2011 - BioPharm International

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BioPharm International Supplements, November 2011
Features
A Brief History of Single-Use Manufacturing
By Jerold Martin
Single-use manufacturing may seem like a new trend, but it has actually been around for almost 30 years, beginning in the early 1980s when filter manufacturers began to make small process-scale plastic filter capsules to replace "junior" size stainless-filter housing assemblies.
Emerging Bioprocessing Methods
By Sarfaraz K. Niazi
New technology is designed to improve production efficiency by taking advantage of the properties of single-use bags.
The Evolution from Fixed to Single-Use Systems
By Gary M. Dennis , Charles Weidner , Saeid Zerafati
An overview of applications for disposable components and important property considerations.
Approaches for Flexible Manufacturing Facilities in Vaccine Production
By Kim L. Nelson
With careful analysis to mitigate risk, disposable technology and process closure can enable adaptable designs and reduced costs.
An Environmental Life Cycle Assessment Comparing Single-Use and Conventional Process Technology
By Matthew Pietrzykowski , William Flanagan , Vincent Pizzi , Andrew Brown , Andrew Sinclair , Miriam Monge
The authors compare the environmental impact of monoclonal antibody production using fixed-in-place processing and single-use systems.

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