BioPharm International Supplements, June 2009 - BioPharm International

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BioPharm International Supplements, June 2009
Articles
Using Metabolic Profiling Technology to Advance Cell Culture Development
By Michael Milburn
Through metabolomics, the metabolic underpinnings of cellular changes can be rapidly pinpointed, directing process development scientists to key areas for cell culture optimization.
Managing Cell Line Instability and Its Impact During Cell Line Development
By Robin A. Heller-Harrison , Kerstin Crowe , Cecilia Cooley , Megan Hone , Kevin Mccarthy , Mark Leonard
By considering stability as part of the cell line selection and cell banking paradigm, we can ensure that instability problems are not observed during clinical or commercial manufacturing.
The Impact of Cell Culture Medium on Cell Line and Process Development Timelines and Strategies
By Alahari Arunakumari, PhD , Xiao-Ping Dai, PhD , Joel Goldstein, PhD , Claudia Kloth, PhD , Haile Ghebremariam , Glenn MacIsaac , Melissa Wagner
ACF medium sped up cell-line development.
Production Strategies for Antibody Fragment Therapeutics
By J.M. Liddell, PhD
Microbial systems such as E. Coli and yeasts are most effective for producing antibody fragments.
Advertisers in This Issue
Lonza
Mallinckrodt Baker
Bioengineering AG
Millipore
New Brunswick Scientific
Innovatis
Scarab Genomics
Glen Mills
Applikon
Pfenex
Althea
Millipore Celliance
Xcellerex
Grenier Bio-One

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