AbSoluteÂ® High Cap is a new generation protein A media based on modified silica particles, specially designed to capture monoclonal and polyclonal antibodies from high titer and large volume fermentation feedstock. This article outlines the outstanding performance of AbSoluteÂ® High Cap which allows a significant reduction in the volume of media required for separation and, as a result, significant cost savings.
Using a pre-sanitized disposable TFF membrane in the DSP of biopharmaceuticals makes it possible to reduce labor by 50% and buffer/water usage by 75%. In addition, it can increase productivity by more than 45%. This economic model compares the costs of reusable and single-use TFF in biopharmaceutical applications.