Articles by Stephan Koza - BioPharm International

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Articles by Stephan Koza

Stephan Koza


PEGylated Protein Analysis by Size-Exclusion and Reversed-Phase UPLC
September 30, 2014

The first PEGylated biotherapeutic, pegademase, which is a bioconjugate of the bovine derived enzyme adenosine deaminase and 5 KDa molecular weight (MW) polyethylene glycol (PEG), was introduced in 1990. Pegademase is used for the treatment of individuals with severe combined immunodeficiency disease (SCID).

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