Tosoh Bioscience

TOYOPEARL GigaCap Q-650S is capable of delivering oligonucleotides of comparable purity to that seen with the TSKgel^® SuperQ-5PW (20) resin and at slightly higher process yields under the same loading conditions but at lower pressures.

TOYOPEARL GigaCap DEAE-650M, a very high capacity anion exchange resin for process scale chromatography, offers chromatographers a combination of binding capacities greater than 150 g/L while maintaining peak resolution.

TOYOPEARL GigaCap DEAE-650M is an ideal anion exchange resin for the chromatographic purification of biotherapeutic products. Since the TOYOPEARL GigaCap DEAE-650M has such a high dynamic binding capacity, the need for very large columns and massive buffer consumption is minimized, particularly for proteins expressed at higher levels due to upstream improvements.

TOYOPEARL MX-Trp-650M, a mixed-mode chromatography resin for process scale chromatography, offers chromatographers selectivity and salt tolerance combined with binding capacities that are similar to traditional cation exchange resins.

TOYOPEARL MX-Trp-650M, a new, mixed-mode chromatography resin combining a weak cation exchange and a hydrophobic ligand is the latest addition to the TOYOPEARL product line.

TOYOPEARL AF-rProtein A-650F was designed for use in mAb purifications. This paper demonstrates the excellent kinetics, superior dynamic binding capacity at very fast flow rates, selectivity and alkaline stability of this resin.

This whitepaper describes TOYOPEARL MX-Trp-650M, a new, mixed mode resin for protein capture. Buffer strengths of 0.20 mol/L NaCl can be used with dynamic binding capacities of up to 90 g/L achieved.

The paper will describe the key performance attributes of TOYOPEARL MX-Trp-650M Mixed-Mode resin and its ability to retain protein capacity even when encountering elevated feedstock or buffer conductivities.

The paper will describe the key performance attributes of TOYOPEARL MX-Trp-650M Mixed-Mode resin and its ability to retain protein capacity even when encountering elevated feedstock or buffer conductivities.