Articles by Uwe Gottschalk, PhD - BioPharm International

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Articles by Uwe Gottschalk, PhD

Uwe Gottschalk, PhD


Vice President of Purification Technologies at Sartorius Stedim Biotech GmbH. He is also a member of BioPharm International's Editorial Advisory Board.

Articles
The Future of Downstream Processing-2013
August 2, 2013

As constant scale up grows out of favor in the biopharmaceutical industry, new—and old—approaches are required. The author reviews the state of downstream processing and considers potential solutions, including the streamlining of full processes and borrowed technologies

A Renaissance in Biomanufacturing: The Art of Purification
August 2, 2013

The industry needs to embrace innovation to improve the efficiency and robustness of biopharmaceutical purification without driving up the cost of goods.

The Future of Downstream Processing
September 1, 2011

The author reviews the state of downstream processing, including a look at the streamlining of full processes and borrowed technologies.

Innovation and the Art of Downstream Processing
April 2, 2011

This summary provides an introduction to our special issue on Separation and Purification.

Technical and Economic Benefits of Membrane Chromatography During Polishing Steps
August 1, 2010

An analysis of flow rate, load density, viral clearance, and cost.

Salt Tolerant Interaction Chromatography for Large-Scale Polishing with Convective Media
October 2, 2009

STIC allows polishing to be carried out without an interstitial dilution step, which reduces process time and avoids additional buffer preparation and hold steps.

Antibody Purification Using Membrane Adsorbers
October 2, 2009

A membrane adsorber in retention mode can be used efficiently in a commercial antibody manufacturing process.

Antibody Purification Using Membrane Adsorbers
December 1, 2008

Results from a process developed for a commercial antibody.

Disposable Decisions
October 1, 2008

To achieve the right balance between disposable and reuseable options, companies must consider important technical and economic factors.

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