Articles by Ashutosh Sharma - BioPharm International



Articles by Ashutosh Sharma

Ashutosh Sharma

Process Development Engineer

Ashutosh Sharma is a process development engineer at Amgen, Inc.

Filter Clogging Issues in Sterile Filtration
April 1, 2008

A case study investigated the root cause of failures in sterile filtration by evaluating the effects and interactions of four operating parameters.

Applying Process Analytical Technology to Biotech Unit Operations
August 1, 2006

Case studies were run to test Process Analytical Technology applications for protein refolding, diafiltration, and cation exchange chromatography. It is shown that it is feasible to design control schemes that rely on measurement of product quality attributes and thereby enable real-time decisions.



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