Articles by St John Skilton, PhD - BioPharm International

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Articles by St John Skilton, PhD

Capturing Conformational Changes in Biotherapeutics by Hydrogen Deuterium Exchange and UHPLC–MS

By providing information on the relative accessibility of locations within a protein, HDX by mass spectrometry opens new windows into the higher order structure of biomolecules.
Aug 2, 2010

By providing information on the relative accessibility of locations within a protein, HDX by mass spectrometry opens new windows into the higher order structure of biomolecules.

Rapid Assessment of Molecular Similarity between a Candidate Biosimilar and an Innovator Monoclonal Antibody Using Complementary LC–MS Methods

Intact protein LC–MS detected a mass variance of 62 Da and peptide mapping located a difference of two amino acids.
Aug 2, 2010

Intact protein LC–MS detected a mass variance of 62 Da and peptide mapping located a difference of two amino acids.

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