Articles by Hongwei Xie, PhD - BioPharm International

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Articles by Hongwei Xie, PhD

Rapid Assessment of Molecular Similarity between a Candidate Biosimilar and an Innovator Monoclonal Antibody Using Complementary LC–MS Methods

Intact protein LC–MS detected a mass variance of 62 Da and peptide mapping located a difference of two amino acids.
Aug 2, 2010
By: Martin Gilar, PhD, Hongwei Xie, PhD, Asish Chakraborty, PhD, Joomi Ahn, Ying Qing Yu, PhD, Weibin Chen, PhD, St John Skilton, PhD, Jeffery R. Mazzeo, PhD, Deepalakshmi P. Dakshinamoorthy

Intact protein LC–MS detected a mass variance of 62 Da and peptide mapping located a difference of two amino acids.

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