Articles by Uwe Gottschalk, PhD - BioPharm International

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Articles by Uwe Gottschalk, PhD

The Future of Downstream Processing

The author reviews the state of downstream processing, including a look at the streamlining of full processes and borrowed technologies.
Sep 1, 2011

The author reviews the state of downstream processing, including a look at the streamlining of full processes and borrowed technologies.

Innovation and the Art of Downstream Processing

This summary provides an introduction to our special issue on Separation and Purification.
Apr 2, 2011

This summary provides an introduction to our special issue on Separation and Purification.

Technical and Economic Benefits of Membrane Chromatography During Polishing Steps

An analysis of flow rate, load density, viral clearance, footprint, and cost.
Aug 1, 2010

An analysis of flow rate, load density, viral clearance, and cost.

Antibody Purification Using Membrane Adsorbers

A membrane adsorber in retention mode can be used efficiently in a commercial antibody manufacturing process.
Oct 2, 2009

A membrane adsorber in retention mode can be used efficiently in a commercial antibody manufacturing process.

Salt Tolerant Interaction Chromatography for Large-Scale Polishing with Convective Media

STIC allows polishing to be carried out without an interstitial dilution step, which reduces process time and avoids additional buffer preparation and hold steps.
Oct 2, 2009

STIC allows polishing to be carried out without an interstitial dilution step, which reduces process time and avoids additional buffer preparation and hold steps.

Antibody Purification Using Membrane Adsorbers

Results from a process developed for a commercial antibody.
Dec 1, 2008

Results from a process developed for a commercial antibody.

Disposable Decisions

To achieve the right balance between disposable and reuseable options, companies must consider important technical and economic factors.
Oct 1, 2008

To achieve the right balance between disposable and reuseable options, companies must consider important technical and economic factors.

Process Chromatography: Five Decades of Innovation

Oct 1, 2007

Low-pressure process chromatography could not have developed without immense efforts to resolve scale-up issues in both column design and matrix stability.

INTRODUCTION: Advances in Process Chromatography The past, present, and possible future of process-scale chromatography

Feb 2, 2007

These articles encapsulate the past, present, and possible future of process-scale chromatography in biopharmaceutical production.

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