The author reviews the state of downstream processing, including a look at the streamlining of full processes and borrowed technologies.
Sep 1, 2011
By:
Uwe Gottschalk, PhD
The author reviews the state of downstream processing, including a look at the streamlining of full processes and borrowed technologies.
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This summary provides an introduction to our special issue on Separation and Purification.
Apr 2, 2011
By:
Uwe Gottschalk, PhD
This summary provides an introduction to our special issue on Separation and Purification.
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An analysis of flow rate, load density, viral clearance, footprint, and cost.
Aug 1, 2010
By:
Nathalie Frau, PhD, Janice Lim, PhD, Andrew Sinclair, Uwe Gottschalk, PhD
An analysis of flow rate, load density, viral clearance, and cost.
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A membrane adsorber in retention mode can be used efficiently in a commercial antibody manufacturing process.
Oct 2, 2009
By:
Leonardo Giovannoni, PhD, Marco Ventani, Uwe Gottschalk, PhD
A membrane adsorber in retention mode can be used efficiently in a commercial antibody manufacturing process.
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STIC allows polishing to be carried out without an interstitial dilution step, which reduces process time and avoids additional buffer preparation and hold steps.
Oct 2, 2009
By:
Rene Faber, PhD, Yujing Yang, PhD, Uwe Gottschalk, PhD
STIC allows polishing to be carried out without an interstitial dilution step, which reduces process time and avoids additional buffer preparation and hold steps.
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To achieve the right balance between disposable and reuseable options, companies must consider important technical and economic factors.
Oct 1, 2008
By:
Uwe Gottschalk, PhD
To achieve the right balance between disposable and reuseable options, companies must consider important technical and economic factors.
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Oct 1, 2007
By:
John Curling, Uwe Gottschalk, PhD
Low-pressure process chromatography could not have developed without immense efforts to resolve scale-up issues in both column design and matrix stability.
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Feb 2, 2007
By:
Uwe Gottschalk, PhD
These articles encapsulate the past, present, and possible future of process-scale chromatography in biopharmaceutical production.
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