Articles by Ashutosh Sharma - BioPharm International

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Articles by Ashutosh Sharma

Filter Clogging Issues in Sterile Filtration

Apr 1, 2008

A case study investigated the root cause of failures in sterile filtration by evaluating the effects and interactions of four operating parameters.

Applying Process Analytical Technology to Biotech Unit Operations

Aug 1, 2006

Case studies were run to test Process Analytical Technology applications for protein refolding, diafiltration, and cation exchange chromatography. It is shown that it is feasible to design control schemes that rely on measurement of product quality attributes and thereby enable real-time decisions.

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