Articles by Tom Wheat, Ph.D. - BioPharm International

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Articles by Tom Wheat, Ph.D.

Quantitative Aspects of UPLC Peptide Mapping

Jul 23, 2007

Throughout the development of a biopharmaceutical protein, peptide mapping is used to demonstrate genetic stability and to confirm the intergrity of the protein. This whitepaper focuses on the quantitative aspects of UPLC peptide mapping with UV detection.

Next Generation Peptide Mapping with Ultra Performance Liquid Chromatography

UPLC achieves better resolution, speed, and sensitivity than HPLC by using 1.7 žm particles and optimized instrumentation.
Jan 1, 2006

Ultra performance liquid chromatography (UPLC) is a new category of liquid chromatography that researchers are using to increase resolution, speed, and sensitivity in a variety of applications. These benefits result from packing columns with 1.7 ?m particles and using instruments that are optimized for such columns.

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