An Integrated Prefilled Syringe Platform Approach for Vaccine Development - The authors describe a holistic and integrated approach to focus on the linkage of the prefilled syringe. - BioPharm

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An Integrated Prefilled Syringe Platform Approach for Vaccine Development
The authors describe a holistic and integrated approach to focus on the linkage of the prefilled syringe.


BioPharm International
Volume 23, Issue 6, pp. 22-29

CONCLUSION

A holistic and integrated prefilled syringe platform toolbox approach will streamline development with higher probability of success even in the complex and challenging case of vaccine products. More importantly, such an approach is not only beneficial to technical challenges, but also provides economic benefits. We sincerely hope that the cost of innovation for a new prefilled syringe system is not so prohibitive that vaccine products cannot afford to achieve the intended health impact to society.

ACKNOWLEDGMENTS

We like to thank Anna Coslovi and Francesca Beccai for their preliminary results to characterize the charge heterogeneity of glycoconjugate vaccines.

Kingman Ng is head, Ronald Malone is principal scientist, Changyun Xiong is scientist II, and Xuefeng Yi is senior scientific associate, all at Pharmaceutical Sciences, Novartis Vaccines and Diagnostics, Inc.,
.

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Peer Reviewed

Article submitted: March 5, 2013. Article accepted: May 1, 2013


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