Throughout BioPharm International's 25th Anniversary Year, 2012, we will be rewinding to articles published in the journal's first volume to see where and how technologies have changed in the past couple of decades as well as what the industry may look forward to. Here, Mike Ultee, chief scientific officer of Laureate Biopharmaceutical Services and member of BioPharm International’s editorial advisory board, discusses advances in separations technology, beginning with the 1988 publication of “Separations Technology Outlook, Part II” by Nancy E. Pfund and Kathleen G. Charles. (Posted January 2012).