Podcast: Sutro Biopharma and Cell-Free Protein Expression Systems - - BioPharm International

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Podcast: Sutro Biopharma and Cell-Free Protein Expression Systems


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In this first of three podcast interviews, Dr. Hallam, chief scientific officer at Sutro Biopharma, introduces a non-traditional approach for expressing therapeutic proteins and peptides. More specifically, Sutro has developed a proprietary technology for manufacturing proteins in a cell-free system. The system uses a cell extract that contains the necessary machinery for producing protein without the need to maintain cell viability. Essentially, the bioreactor is the cell membrane for a giant cytosolic preparation. Dr. Hallam talks about the advantages of the system and even speculates as to future applications, for example, in a biodefense scenario. Posted Nov. 2011.

Related article on industrializing design, development, and manufacturing of therapeutic proteins

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