The Future of Downstream Processing - The author reviews the state of downstream processing, including a look at the streamlining of full processes and borrowed technologies. - BioPharm International

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The Future of Downstream Processing
The author reviews the state of downstream processing, including a look at the streamlining of full processes and borrowed technologies.


BioPharm International
Volume 24, Issue 9, pp. 38-47

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13. S. Vunnum, G. Vedantham, and B. Hubbard "Protein A-based Affinity Chromatography," in Process Scale Purification of Antibodies, U. Gottschalk, Ed. (Wiley, NY, 2009), pp. 79–102.

14. J. Glynn et al., "The Development and Application of a Monoclonal Antibody Purification Platform," supplement to Biopharm. Int. (2009).

15. J. Glynn et al., "Development of a MAb Harvest Protocol", proceedings of Biochemical Engineering XV: Engineering Biology from Biomolecules to Complex Systems (Quebec City, Canada, 2007) pp 15–19.

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17. J. Thömmes and U. Gottschalk, "Alternatives to Packed-bed Chromatography for Antibody Extraction and Purification," in Process-scale Purification of Antibodies, U. Gottschalk, Ed. (Wiley, NY, 2009) pp. 293–308.

18. A.A. Shulka and J.R. Kandula, "Harvest and recovery of monoclonal antibodies: Cell Removal and Clarification" in Process-scale Purification of Antibodies, U. Gottschalk, Ed. (Wiley, NY 2009) pp. 53–78.

19. R. Shpritzer et al., presentation at 232nd ACS National Meeting (San Francisco CA, 2006).

20. J. Glynn, "Process Scale Precipitation of Impurities in Mammalian Cell Culture Broth," in Process-scale Purification of Antibodies, U. Gottschalk, Ed. (Wiley, NY, 2009) pp. 309–324.


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