Analysis of PEGylated Protein by Tetra Detection Size Exclusion Chromatography - Reliably detecting low amounts of high molecular weight impurities during process development and characterization of b

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Analysis of PEGylated Protein by Tetra Detection Size Exclusion Chromatography
Reliably detecting low amounts of high molecular weight impurities during process development and characterization of biopharmaceutical products.


BioPharm International Supplements
Volume 24, Issue 8, pp. s10-s14

REFERENCES

1. B.S. Kendrick et al., Anal. Biochem. 299 (2), 136–46 (2001).

2. J. Wen, T. Arakawa and J.S. Philo, Anal. Biochem. 240 (2), 155–166 (1996).

3. M. Kunitani and L. Kresin, J. Chromatogr. 632 (1–2), 19–28 (1993).

4. B.H. Zimm, J. Chem. Phys. 16 (12), 1099–116 (1948).

5. Cantor and Schimmel, "Other Hydrodynamic Techniques," in Biophysical Chemistry, Part II: Techniques for the study of biological structure and function (W.H. Freeman and Company, NY, 1st ed., 1980), p. 650-653.

6. C. Fee and J.M. Van Alstine, Bioconj. Chem. 15 (6), 1304–1313 (2004).

7. M.W.F. Neilen, Mass Spec. Rev. 18 (5), 309-344 (1999).

8. A.B. Chakraborty, W. Chen and J.C. Gebler, Pharm. Technol. 32 (7), 80–87 (2008).

9. K.J. Liu, Macromol. Chem. Phys. 116 (1), 146–151 (1968).

10. S. Krishnan et al., Biochemistry 41 (20), 6422–6431 (2002).

11. R.S. Rajan et al., Prot. Sci. 15 (5), 1063–1075 (2006).

12. T. Arakawa et al., J. Pharm. Sci. 99 (4), 1674–1692 (2010).


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