Analysis of PEGylated Protein by Tetra Detection Size Exclusion Chromatography - Reliably detecting low amounts of high molecular weight impurities during process development and characterization of b

ADVERTISEMENT

Analysis of PEGylated Protein by Tetra Detection Size Exclusion Chromatography
Reliably detecting low amounts of high molecular weight impurities during process development and characterization of biopharmaceutical products.


BioPharm International Supplements
Volume 24, Issue 8, pp. s10-s14

REFERENCES

1. B.S. Kendrick et al., Anal. Biochem. 299 (2), 136–46 (2001).

2. J. Wen, T. Arakawa and J.S. Philo, Anal. Biochem. 240 (2), 155–166 (1996).

3. M. Kunitani and L. Kresin, J. Chromatogr. 632 (1–2), 19–28 (1993).

4. B.H. Zimm, J. Chem. Phys. 16 (12), 1099–116 (1948).

5. Cantor and Schimmel, "Other Hydrodynamic Techniques," in Biophysical Chemistry, Part II: Techniques for the study of biological structure and function (W.H. Freeman and Company, NY, 1st ed., 1980), p. 650-653.

6. C. Fee and J.M. Van Alstine, Bioconj. Chem. 15 (6), 1304–1313 (2004).

7. M.W.F. Neilen, Mass Spec. Rev. 18 (5), 309-344 (1999).

8. A.B. Chakraborty, W. Chen and J.C. Gebler, Pharm. Technol. 32 (7), 80–87 (2008).

9. K.J. Liu, Macromol. Chem. Phys. 116 (1), 146–151 (1968).

10. S. Krishnan et al., Biochemistry 41 (20), 6422–6431 (2002).

11. R.S. Rajan et al., Prot. Sci. 15 (5), 1063–1075 (2006).

12. T. Arakawa et al., J. Pharm. Sci. 99 (4), 1674–1692 (2010).


blog comments powered by Disqus

ADVERTISEMENT

ADVERTISEMENT

Compounding Pharmacy Issues Recall, But Challenges FDA Decision
July 22, 2014
AbbVie's Acquisition of Shire Could Save $8 Billion in Taxes
July 21, 2014
AstraZeneca Reveals Design for New Global R&D Center and Corporate Headquarters
July 18, 2014
AbbVie to Acquire Shire for $54.7 Billion
July 18, 2014
Particulate Matter Prompts Baxter's Recall of IV Solutions
July 17, 2014
Author Guidelines
Source: BioPharm International Supplements,
Click here