Analysis of PEGylated Protein by Tetra Detection Size Exclusion Chromatography - Reliably detecting low amounts of high molecular weight impurities during process development and characterization of b

ADVERTISEMENT

Analysis of PEGylated Protein by Tetra Detection Size Exclusion Chromatography
Reliably detecting low amounts of high molecular weight impurities during process development and characterization of biopharmaceutical products.


BioPharm International Supplements
Volume 24, Issue 8, pp. s10-s14

REFERENCES

1. B.S. Kendrick et al., Anal. Biochem. 299 (2), 136–46 (2001).

2. J. Wen, T. Arakawa and J.S. Philo, Anal. Biochem. 240 (2), 155–166 (1996).

3. M. Kunitani and L. Kresin, J. Chromatogr. 632 (1–2), 19–28 (1993).

4. B.H. Zimm, J. Chem. Phys. 16 (12), 1099–116 (1948).

5. Cantor and Schimmel, "Other Hydrodynamic Techniques," in Biophysical Chemistry, Part II: Techniques for the study of biological structure and function (W.H. Freeman and Company, NY, 1st ed., 1980), p. 650-653.

6. C. Fee and J.M. Van Alstine, Bioconj. Chem. 15 (6), 1304–1313 (2004).

7. M.W.F. Neilen, Mass Spec. Rev. 18 (5), 309-344 (1999).

8. A.B. Chakraborty, W. Chen and J.C. Gebler, Pharm. Technol. 32 (7), 80–87 (2008).

9. K.J. Liu, Macromol. Chem. Phys. 116 (1), 146–151 (1968).

10. S. Krishnan et al., Biochemistry 41 (20), 6422–6431 (2002).

11. R.S. Rajan et al., Prot. Sci. 15 (5), 1063–1075 (2006).

12. T. Arakawa et al., J. Pharm. Sci. 99 (4), 1674–1692 (2010).


blog comments powered by Disqus

ADVERTISEMENT

ADVERTISEMENT

Bristol-Myers Squibb and Celgene Collaborate on Immunotherapy and Chemotherapy Combination Regimen
August 20, 2014
USP Center in Ghana Receives International Lab Accreditation
August 15, 2014
USP Awards Analytical Research
August 15, 2014
FDA Warns about Fraudulent Ebola Treatments
August 15, 2014
Guilty Plea to Importing Illegal Cancer Drugs
August 15, 2014
Author Guidelines
Source: BioPharm International Supplements,
Click here