Applying Computational Fluid Dynamics Technology in Bioprocesses-Part 1 - Computational fluid dynamics is a powerful tool to optimize processes. - BioPharm International

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Applying Computational Fluid Dynamics Technology in Bioprocesses-Part 1
Computational fluid dynamics is a powerful tool to optimize processes.


BioPharm International
Volume 23, Issue 4

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30. Yeoh SL, Papadakis G, Yianneskis M. Numerical simulation of turbulent flow characteristics in a stirred vessel using the LES and RANS approaches with the sliding/deforming mesh methodology. Chem Eng Res Des. 2004;82(7):834–48.

31. Hartmann H, Derksen JJ, Montavon C, Pearson J, Hamill IS, van den Akker HEA. Assessment of large eddy and RANS stirred tank simulations by means of LDA. Chem Eng Sci. 2004;59(12):2419–32.

32. Derksen JJ, Kontomaris K, McLaughlin JB, Van den Akker HEA. Large-eddy simulation of single-phase flow dynamics and mixing in an industrial crystallizer. Chem Eng Res Des. 2007;85(2):169–79.

33. Delafosse A, Line A, Morchain J, Guiraud P. LES and URANS simulations of hydrodynamics in mixing tank: Comparison to PIV experiments. Chem Eng Res Des. 2008;86(12):1322–30.

34. Sommerfeld M, Decker S. State of the art and future trends in CFD simulation of stirred vessel hydrodynamics. Chem Eng Tech. 2004;27(3):215–24.

35. Xia JY, Wang YH, Zhang SL, Chen N, Yin P, Zhuang YP, et al. Fluid dynamics investigation of variant impeller combinations by simulation and fermentation experiment. Biochem Eng J 2009;43(3):252–60.

36. Harris CK, Roekaerts D, Rosendal FJJ, Buitendijk FGJ, Daskopoulos P, Vreenegoor AJN, et al. Computational fluid dynamics for chemical reactor engineering. Chem Eng Sci. 1996;51(10):1569–94.

37. Aubin J, Fletcher DF, Xuereb C. Modeling turbulent flow in stirred tanks with CFD: the influence of the modeling approach, turbulence model and numerical scheme. Exper Therm Fluid Sci. 2004;28(5):431–45.

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