Manufacturing Vaccines in Adherent Cell Lines Using Disposable Multi-tray Bioreactors - By allowing a single system to be used from laboratory- to commercial-scale, multi-tray bioreactors can facilita

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Manufacturing Vaccines in Adherent Cell Lines Using Disposable Multi-tray Bioreactors

By allowing a single system to be used from laboratory- to commercial-scale, multi-tray bioreactors can facilitate scale up and accelerate vaccine development.

Aug 2, 2007
By: Edwin Schwander
BioPharm International

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References:

1 Cesano A, Visonneau S, Jeglum KA, Owen J, Wilkinson K, Carner K, et al. Phase i clinical trial with a human major histocompatibility complex nonrestricted cytotoxic t-cell line (tall-104) in dogs with advanced tumors. Cancer Res. 1996; 56:3021–3029.

2. Schwander E, Ramusen, H. Manufacturing of lots of human T lymphocytes for cell therapy: A new process based on disposable bioreactors. Gen Eng News. 2005 Apr 15; 25(8).

3. Schlenke P, et al. Serum-free transient expression of antibodies using 40 tray cell factories. Poster. Laupheim, Germany: Renschler Biotechnologie Gmbh.

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