Approaches to BBB delivery include using lipophilic pro-drugs, carrier-mediated transport, inhibition of efflux transporters,
and receptor-mediated transport.41 Given the importance of the CNS area, advances in BBB delivery should have significant impacts on the practice of medicine.
[Editors note: Figures for this article are not available online. To obtain a complete copy of the article with figures,
please send your mailing address to csethi@advanstar.com
].
William J. Lambert, PhD, is the senior vice president of pharmaceutical development at Pacira Pharmaceuticals, Inc. (previously SkyePharma Inc.),
San Diego, CA, 858.625.2424, BillL@pacira.com
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