NEW PLANT CONSTRUCTION
How Disposables Helped Hyclone Save Time and Money
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Constructing a plant that incorporates disposable processing lines can shave several months off build time, during which a
pharmaceutical company could potentially sell $200 million or more in drugs. Disposables require less space than conventional
equipment, and they can be assembled into complete process trains offsite while the core facility is being built. These steps
can reduce total construction time.
CONCLUSION
Biopharmaceutical equipment suppliers recognize that disposable processing is the paradigm of the future, and they are pouring
resources into developing new single-use technologies for both upstream and downstream processes. The recent introduction
of a new disposable bioreactor based on shake mixing is an example of this. On the downstream side, many single-use innovations
are being unveiled in the areas of tangential flow filtration and membrane chromatography.
Quick Recap
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As stand-alone disposable devices become integrated into multi-component assemblies, the time to market and cost-saving benefits
increase significantly. Today's availability of disposable products is poised to turn single-use process trains into completely
disposable factories.
Hélène Pora is marketing director, Pall Life Sciences, Pall France, 3 rue des Gaudines - B.P. 5253, 78175 Saint Germain-en-Laye Cedex-France, tel. +33.1.3061.32.20, fax 33.1.30.51.57.08,
hpora@pall.com
REFERENCES
1. BioPlan Associates. Barre's 3rd Annual Report and Survey on BioPharmaceutical Manufacturing: Rockville, MD 2005.
2. "Outsourcing to Show Healthy Growth in Pharma."Business Communications' Pharmaceutical Contract Manufacturing and Research
report cited in
http://In-Pharmatechnologist.com/, March 3, 2005, http://
http://www.inpharmatechnologist.com/news/ng.asp?n=58484-outsourcing-to-show/
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