UPLC System for Nano- to Microscale Separations - - BioPharm International

ADVERTISEMENT

UPLC System for Nano- to Microscale Separations


BioPharm International
Volume 27, Issue 3, pp. 64

Waters’ Acquity UPLC M-Class System, a nano- to microscale UPLC system rated for 15,000 psi operation, delivers the sensitivity to quantify and identify small concentrations of key molecules. The system is suited for applications including proteomics, metabolic profiling, metabolite identification, and pharmacokinetic studies. The 15k psi-capable Acquity UPLC M-Class columns tap the potential of sub-2-micron particle technology, yielding faster separations, greater peak capacities, and increased levels of sensitivity, the company reports.

A new micro electrospray ionization probe is optimized for microscale separations, along with low-dispersion flow cells that retain chromatographic resolution into the detector. The increased pressure envelope enables the Acquity UPLC M-Class System to exploit fully sub-2-micron particles in longer columns, up to 25 cm in length. The ACQUITY UPLC M-Class System, together with Waters SYNAPT G2-Si or Xevo G2-S QT mass spectrometers, delivers the spectral data required to resolve the small mass changes typical in hydrogen deuterium exchange mass spectrometry.

Waters

blog comments powered by Disqus

ADVERTISEMENT

ADVERTISEMENT

FDA Extends Review of Novartis' Investigational Compound for Multiple Myeloma
November 25, 2014
Merck Enters into Licensing Agreement with NewLink for Investigational Ebola Vaccine
November 25, 2014
AstraZeneca Expands Biologics Manufacturing in Maryland
November 25, 2014
GSK Leads Big Pharma in Making Its Medicines Accessible
November 24, 2014
IMS: Global Spending on Medicines to Rise 30% by 2018
November 24, 2014
Author Guidelines
Source: BioPharm International,
Click here