Cellectis Enters Agreement With CELLforCURE - - BioPharm International

ADVERTISEMENT

Cellectis Enters Agreement With CELLforCURE



Cellectis, a company focused on the development of adoptive immunotherapies based on engineered allogeneic Universal Chimeric Antigen Receptor T-cells (UCART) and CELLforCURE, a subsidiary of the biopharmaceutical group LFB, have entered into an agreement in which CELLforCURE will be responsible for the cGMP manufacturing of clinical batches of Cellectis’ allogeneic CART cells. CELLforCURE operates a commercial industrial facility for the production of new therapeutic cell therapies in Les Ulis, France.

The candidates from the UCART product family are allogeneic cell therapy products based on the CAR (Chimeric Antigen Receptor) technology combined with genome engineering. According to the company, engineered allogeneic T-lymphocytes bearing a CAR directed at a tumor antigen are a new potential treatment for the various forms of leukemias, lymphomas, and solid tumors. UCARTs are “off-the-shelf” allogeneic products, which means that UCART production can be standardized, with consistent pharmaceutical release criteria, over time and from batch to batch. The favorable cost of such industrially manufactured treatments may help make them available to a broad patient population and avoid risks associated with the processing and the timing required for an autologous CART process.

Source: Cellectis

blog comments powered by Disqus

ADVERTISEMENT

ADVERTISEMENT

GPhA Supports Restricted Access Bill
September 18, 2014
Baxter Initiates Voluntary Recall of Potassium Chloride Injection
September 17, 2014
European Commission Approves RoACTEMRA for Treatment of RA
September 9, 2014
PDA Announces Technical Report on Drug Shortages
September 9, 2014
Infinity and AbbVie Collaborate to Develop Oncology Drug
September 5, 2014
Author Guidelines

Click here