Sponsored Whitepapers

Apr 19, 2018
Sponsored Content
Antibody Affinity Extraction (AAE) is a superior alternative to 2D Western blot for demonstrating host cell protein (HCP) antibody coverage and reactivity to those HCPs that persist through the downstream purification process.
Apr 17, 2018
Sponsored Content
The data presented here demonstrate the effectiveness of TOYOPEARL GigaCap S-650M, TOYOPEARL GigaCap S-650S and TOYOPEARL GigaCap CM-650M resins in the elimination of mAb aggregates from protein A purified material.
Apr 04, 2018
Sponsored Content
Hydrophobic interaction chromatography (HIC) is used for the determination of drug-to-antibody ratio (DAR) of a cysteine-linked antibody drug conjugate (ADC).
Mar 19, 2018
Sponsored Content
TOYOPEARL AF-rProtein A HC-650F is capable of delivering high purity monoclonal antibodies with excellent recovery at loading levels approaching the resin capacity in columns with bed heights as short as 4.2 cm without any increase in aggregate levels or loss of product yield.
Mar 08, 2018
Sponsored Content
Peak-based fraction collection of the cysteine linked antibody-drug conjugate (ADC) brentuximab vedotin is performed after hydrophobic interaction chromatography (HIC).
Mar 08, 2018
Sponsored Content
Peak-based fraction collection of the cysteine linked antibody-drug conjugate (ADC) brentuximab vedotin is performed after hydrophobic interaction chromatography (HIC).
Feb 22, 2018
Sponsored Content
Optimizing purification conditions is an essential step prior to automating multicolumn purification. Save time performing mAb purifications with the NGC Chromatography System to find your ideal conditions in hours or days versus weeks.
Feb 22, 2018
Sponsored Content
TOYOPEARL AF-rProtein A HC-650F is capable of delivering high purity monoclonal antibodies with excellent recovery at loading levels approaching the resin capacity in columns with bed heights as short as 4.2 cm without any increase in aggregate levels or loss of product yield.
Jan 18, 2018
Sponsored Content
Detection and quantification of peptides from transmembrane proteins is important for detection of biomarkers and new protein based drugs. This paper presents a fully automated online digestion and liquid chromatography-mass spectrometry-multiple reaction monitoring (LCMS MRM) analysis of two model transmembrane proteins, a method that improves reproducibility and decreases chances of contamination.
Jan 18, 2018
Sponsored Content
In the pharmaceutical industry, speed to market is essential for gaining a competitive position. New encapsulation technologies now make it possible to streamline research and development activities, improve product development, and jump-start time to market.
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